Temporin-GHa (GHa) was cloned from Hylarana guentheri, showing a weak antimicrobial activity.In order to improve its bactericidal efficacy, GHaR6R, GHaR7R, GHaR8R and GHaR9W were designed and synthesized.Compared to the parent peptide, the GHa-derived peptides Gloves show potent antimicrobial activities against methicillin-resistant Staphylococcus
Study regions: The Rovte region, Central Slovenia, is a rural region where karst spring waters are often used for drinking water consumption and irrigation.Study focus: In karst regions, water quickly reaches the subsurface through features ranging from thin fractures to large conduits; as such, this rapid flow leaves karst areas particularly vulne
Synthesis of the capsular polysaccharide, a major virulence factor for many pathogenic bacteria, is required for bacterial survival within the infected host.In Streptococcus pneumoniae, Wze, an autophosphorylating tyrosine kinase, and Wzd, a membrane protein required for Wze autophosphorylation, co-localize at the BODY OIL division septum and guara
Although T-cell infiltration is correlated with EMT-related gene expression in COLOR PROTECT LOCKING SPRAY urothelial cancer specimens, here, the authors report EMT-related signatures in urothelial cancer arise mainly from stromal cells.Increased EMT-related gene expression Accessories in T-cell infiltrated tumors is associated with an attenuated r